Are organ donors really dead?

BioEdge

Xavier Symons

What does it mean for a human being to “die”? This question is more complex than one might think. In the domain of vital organ procurement, there is significant disagreement about the criteria that we should employ to assess when someone has died.

The standard criterion for several decades has been the “brain death” criterion, according to which a patient can be pronounced dead once “whole brain death” has occurred. Whole brain death refers to the comprehensive and irreversible cessation of brain function, typically caused by trauma, anoxia or tumor.

Yet transplant surgeons have in recent years employed a different, more ethically contentious definition of death, the so-called “circulatory criterion for death”. “Circulatory death” refers to the permanent cessation of cardiopulmonary function, after which point brain tissue quickly begins to deteriorate (if it hasn’t already).

According to proponents of the circulatory criterion, a patient’s heart will never spontaneously restart after 2 or so minutes of pulselessness. As such, it is seen as ethically permissible to begin organ procurement once this short time period has elapsed. There are in practice different time periods specified by healthcare regulators for when organ procurement can begin (typically between 75 seconds and 5 minutes).

Yet several scholars have criticised the cardiopulmonary definition of death, arguing that the impossibility of autoresuscitation does not necessarily indicate that death has occurred. Critics point out that CPR could still restart a person’s heart even when autoresuscitation has become an impossibility.

The most recent criticism came from Kennedy Institute for Ethics bioethicist Robert Veatch, who wrote an extended blog post on the topic this week. Veatch states:

If one opts for requiring physiological irreversibility, death should be pronounced whenever it is physiologically impossible to restore brain function. Autoresuscitation is completely irrelevant. If autoresuscitation can be ruled out before physiological irreversibility, one must still wait until that point is reached. On the other hand, if it becomes physiologically impossible to restore function before autoresuscitation can be ruled out, death can be pronounced at the earlier point. Either way autoresuscitation is irrelevant.


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Doctors find patient brain activity continued for 10 minutes after death

Medical Xpress

Bob Yirka

A team of doctors affiliated with the University of Western Ontario in Canada has documented a case in which a terminal patient removed from life support continued to experience brain wave activity for approximately 10 minutes after they had been pronounced clinically dead. In their paper published in The Canadian Journal of Neurological Sciences, the team describes the circumstances of the unusual event and acknowledge that they have no explanation for what they observed.

For many years, doctors have used a handful of tools to determine if someone has died—a lack of pupil dilation, heart stoppage, lack of breathing, etc. But one test has stood above all others—an EEG reading. Even if the heart is beating and a person is breathing, if the brain stops processing electrical signals, that person is considered clinically dead—though in some cases they may be labeled as brain dead. But what if a person’s heart stops beating, meaning there is no blood flow to the brain, and the brain continues to show delta wave bursts for up to ten minutes? Prior to this event occurring in Canada, it was thought to be an impossibility. . . [Full text]

 

Serious mistake made in diagnosing death before organ transplantation

A 19 year old girl who was seriously injured in a car crash in October, 2011, narrowly escaped having vital organs removed for transplant following what appears to have been a misdiagnosis by attending physicians.  After consulting with the family, they removed a respirator and ceased treatment. However, the girl regained consciousness as they were preparing to harvest her organs. [Medical Daily]